Welcome to Herbodee

Herbodee is dedicated to bring the first human health products containing the active form of vitamin D which is entirely of herbal origin to the market.

Vitamin D

"Vitamin D" consists of a family of exiting compounds which exert similar biological activities: they prevent or heal rickets, as can be quantified in specific bioassays.

But they do more than that:

They control intestinal uptake of calcium and phosphates, their deposition into bone and their mobilization from there, and finally their excretion in the kidneys.

They play a role in cell differentiation and proliferation.

They are relevant for skin, muscle function and possibly immune function.

They might be involved in cancer prevention.


But, there is more than just one compound to discuss:


The most important is vitamin D3 (or cholecalciferol), which is produced by animals and plants.
A lesser role plays also vitamin D2 (or ergocalciferol), which is produced by mushrooms.

In addition, the vitamin D family undergoes complex metabolic transformations to become active.

Vitamin D3 (Cholecalciferol)

Vitamin D3 (cholecalciferol) is produced in humans or animals skin from cholesterol under the impact of sunlight (the uv portion of its spectrum). Therefore, is was also called "the sunshine vitamin".

However, in higher latitudes and especially in winter the body’s own production is not always sufficient, particularly in the elderly. Epidemiologic studies showed an under-supply in different segments of the population, resulting in a sub-optimal concentration of the storage form of the vitamin (see below). This might lead to a sub-clinical deficiency and, in consequence, to potentially higher susceptibility to diseases.

Vitamin D as such is not active, it needs biological activation in the body:

  • Endogenously produced or ingested vitamin D is in the liver quickly converted into the storage form, 25-Hydroxyvitamin D3, with a conversion efficiency of approximately 60%. 25-Hydroxyvitamin D3 is not biologically active and circulates in blood bound to the vitamin D binding protein.
  • The subsequent conversion to the biologically active form, 1α,25-dihydroxyvitamin D3 is almost exclusively located in the kidney, catalyzed by an enzyme complex which adds a second hydroxy group. This conversion step is regulated by a complex system of activating and inhibiting factors ensuring calcium homeostasis. Blood calcium concentration is the principle regulator of this system, because both, too high or too low calcium levels are harmful.

1,25-dihydroxyvitamin D3 (the active form)

Some conditions may result in changes in calcium homeostasis which are too subtle be recognized by the regulatory system, and then even sufficient supplementation with vitamin D or its storage form may result in sufficient supply of the active form. In such cases supplementation with the active form of vitamin D is indicated. Osteoporosis, for example, is such a condition.

Obviously, when kidney function is reduced supplementation of 1,25-dihydroxyvitamin D is also indicated.

D FAQ's

Can be produced in the skin under the impact of sun light. It has been estimated that exposure of face, hands and arms for only 20 minutes per day of provides the minimal daily requirement of the vitamin. Food generally does not contain plenty of the vitamin, and therefore supplementation during winter may be a good alternative.
The term vitamin D describes a family of compounds which show activity in a bioassay for vitamin D (for further reading refer to the AOAC method 936.14 (45.3.02) ) . The most important of the family is vitamin D3 or cholecalciferol, which is produced from cholesterol. Vitamin D2 or ergocalciferol is produced in mushrooms.
The term vitamin D includes both forms.
Is the natural storage form and is produced in the liver by a specific enzyme.
It has no other biologic function.
Is the active form of the vitamin and exerts its effect by binding to the specific vitamin D receptor (VDR), which induces a biological response.

D History

In 1918, Sir Edward Mellanby demonstrated that the disease rickets was caused by a nutritional deficiency by curing rachitic infants with cod liver oil.

the structure of vitamin D3 (Cholecalciferol) was isolated by McCollum in 1922 and named as vitamin D.

Hess, Smith and Steenbock in 1924 confirmed that sunlight is source of vitamin D.

R.B. Woodward awarded noble prize for artificial synthesis of the vitamin in 1965.

Herbodee was founded in September 2017 to develop products for human health and nutrition containing the active form of vitamin D which is entirely of herbal origin.

Our Products

Herbodee is at this time developing several products for the market.


The development pipeline contains:

Solbone® P

a product for human health as a Rx drug

A standardized extract form the plant Solanum glaucophyllum which contains the active vitamin D3 in glycosidic bound form.
It is under development as a prescripion drug.

Trisbone®

a nutritional supplement for human use

a standardized extract from the plant Trisetum flavescens which contains vitamin D active components among other plant ingredients.
It is under development as a food supplement.

Trisderm®

a product for skin care

a standardized extract from the plant Trisetum flavescens which contains vitamin D active components among other plant ingredients.
It is under development as anti-aging ingredient in skin care products.

Investors

Herbodee is seeking investors and partners for developing new business

Private investors

Health companies

Institutional investors


which are interested to invest in innovative, but affordable health products of natural origin.

About Us

Herbodee is a spin-off of Herbonis AG a company specialized in the development of herbal products containing vitamin D active compounds.

Herbodee was established in September 2017 to develop such products for human health and nutrition, while Herbonis AG is covering the animal health and nutrition market.

Links & News

Some links you might be interested in.

2018 International Congress on Vitamin D

2018 International Congress on Vitamin D

The Vitamin D Workshop is a 501c3 non-profit organization that organizes an annual international conference on the biology and health implications of Vitamin D.

Find out more  

Get in Touch

Contact Info

Herbodee AG
Rheinstrasse 30
4302 Augst BL, Switzerland
Office: +41 (0)61 811 52 70